Dengue, NS1

Dengue, NS1

Dengue fever test is a blood test performed to detect the viral fever infection caused by mosquitoes.

Also known as Dengue Fever Antibodies Dengue Fever Virus

Formal Name: Dengue Antibodies (IgG IgM)|Dengue Virus by PCR

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Symptoms:

  • The most common initial symptoms are a sudden high fever (104°F or 40°C) and flu-like symptoms that appear roughly 4 to 7 days after being bitten by an infected mosquito (this is called the incubation period and can range from 3 to 14 days).
  • experiencing fever after travel to a tropical or subtropical destination
  • developed a high fever within 2 weeks of travel to an area where dengue fever is endemic or an outbreak is occurring
  • Additional signs and symptoms may include severe headache, especially behind the eyes, muscle and joint pain, skin rash, nausea, vomiting, and swollen glands.

Dengue fever is usually diagnosed via some combination of blood tests because the body’s immune response to the virus is dynamic and complex. Laboratory tests may include:

  • Molecular tests for dengue virus (PCR)- detect the presence of the virus itself; these tests can diagnose dengue fever up to 7 days after the onset of symptoms and can be used to determine which of the 4 different serotypes of dengue virus is causing the infection.
  • Antibody tests, IgM and IgG- detect antibodies produced by the immune system when a person has been exposed to the virus; these tests are most effective when performed at least 4 days after exposure.
  • Complete blood count (CBC) -to look for low platelet count typical of the later stages of the illness and to detect the decrease in hemoglobin, hematocrit, and red blood cell (RBC) count (evidence of anemia) that would occur with blood loss associated with severe dengue fever
  • Basic metabolic panel (BMP) – to monitor kidney function and look for evidence of dehydration that can occur with severe illness.
  • Result interpretation
  • Molecular testing—a PCR test that detects the presence of the virus itself is generally considered the most reliable means of diagnosis. A positive result from a PCR is considered conclusive. A negative result on a PCR test may indicate that no infection is present or that the level of virus is too low to detect, as may happen if the test was performed after the 7-day window during which the virus is present in the sample collected for this test. A negative PCR result is followed by antibody testing (below).
  • Antibody testing—antibody tests may be reported as positive or negative, or may be reported as an antibody titer with an interpretation of which type(s) of antibody (IgG or IgM) is present.
  • Positive IgM and IgG tests for dengue antibodies detected in an initial blood sample mean that it is likely that the person became infected with dengue virus within recent weeks.
  • IgM antibody tests can be positive if a person has been infected with a similar virus, such as chikungunya (called cross-reaction).
  • If an initial IgM antibody test is positive, a second test called the Plaque Reduction Neutralization Test (PRNT) is used to confirm the presence of antibodies to dengue virus and to help rule out other viral infections.
  • If the IgG is positive but the IgM is low or negative, then it is likely that the person had an infection sometime in the past.
  • If the dengue IgG antibody titer increases four-fold or greater (e.g., titer of 1:4 to a titer of 1:64) between an initial sample and one taken 2 to 4 weeks later, then it is likely that a person has had a recent infection.
  • Negative tests for IgM and/or IgG antibodies may mean that the individual tested does not have a dengue infection and symptoms are due to another cause, or that the level of antibody may be too low to measure. The person may still have a dengue infection – it may just be that it is too soon after initial exposure to the virus to produce a detectable level of antibody.
  • A positive result means you probably have been infected with the dengue virus.
  • A negative result can mean you aren’t infected or you were tested too soon for the virus to show up in testing.

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Why Iris Laboratories?

Irismed Lab has a team of 200 senior pathologists and over 2000 technicians delivering diagnostic solutions in the areas of routine, semi specialty and super specialty domains like Oncology, Neurology, Gynaecology, Nephrology and many more. We offer a comprehensive range of 4000+ clinical laboratory tests and profiles, which are used for prediction, early detection, diagnostic screening, confirmation and/or monitoring of the disease.

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Over 2000+ Scientific Officers

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How is blood sample collected?

There is no known risk involved for removing a small amount of blood from the body.
The phlebotomist:
  • Cleans your arm
  • Inserts a needle (the needle prick may slightly sting or can feel a pinch)
  • Removes the required amount of blood in the syringe
  • And collects the blood in a tube
  • Removes the needle
  • Place a bandage on the arm

Note:

  • Sometimes, more than one tube of blood may be collected depending upon the number of tests to be performed
  • For neonates or infants, needle may be inserted in the heel

Did you know?

Giving a small amount of blood for testing purposes does not harm your body. Your body will quickly rebuild it back in the blood supply. There are more than 100 tests that can be performed that can be correlated with more than hundreds of conditions. To know more, click here.

Frequently Asked Questions

Yes our laboratory is accredited by the NABL (National Accreditation Board of Testing and Calibration of Laboratories) India & College of American Pathologists (CAP). This accreditation process is carried out every 2 years for NABL & annually for CAP with periodic internal audits carried out twice in a year. All our aforementioned tests are accredited by NABL & CAP.
TruHealth is an expert and comprehensive inner health wellness by Metropolis. It helps you monitor and maintain your inner health parameters better, so that you are ready to achieve your dreams, always.Metropolis TruHealth – Because Health is Everything.
SMART report covers a comprehensive view of your lifestyle related diseases and risk analysis, health recommendations, reminders and recommended reflex tests. Get regular communications to monitor and maintain your inner health.
Reports will be delivered on your registered email id with a TAT (Turnaround time) of 24 hours.
We will deliver reports on your email id, check the email received from Metropolis India. You can also download it by signing in to your profile in our website or in TruHealth App
You can select the best health package suited to you based on your gender, age and lifestyle.
Additional Home Visit and Safety charges will be applicable for all test and Health packages.
We collect samples from home between 7:00 AM to 7:00 PM. we offer Blood collection service on Sunday’s as well.
Doctor’s prescription is not required if you avail any wellness package. For any illness test, prescription might be required.
Test samples are processed at our regional laboratories in various cities – Mumbai, Pune, Chennai, Banaglore, Delhi and more. You can check out more information here – Our Labs

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